These calculations are intended for educational use by healthcare professionals. Calculations must be re-checked and should not be used to guide patient care or clinical judgment (Disclaimer).

This tool is based on lipid values obtained from participants of the Lifelines study. Participants with cardiovascular disease or those using lipid lowering therapies were excluded. A total of 133,450 adults (>= 18 years old) and 8,071 children (< years old) were included. Further details are described in:

1. Balder, J. W. et al. J. Clin. Lipidol. 11, 1055-1064.e6 (2017)
2. Balder, J. W. et al. J. Clin. Lipidol. 12, 1208–1216 (2018)
3. Stolk, R. P. et al. Eur. J. Epidemiol. 23, 67–74 (2008)